Human FSH ELISA Kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
- 样品类型:
- 标准范围:
-
Brand:
CAT.NO. : ARG80844
US＄ Please choose
US＄ Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。
Product Details
概述
| 产品描述 | ARG80844 Human FSH ELISA Kit is an enzyme immunoassay kit for the quantification of Follicle Stimulating Hormone (FSH) in serum. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 靶点名称 | FSH / Follicle Stimulating Hormone |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm |
| 灵敏度 | 0.856 mIU/ml |
| 样品类型 | Serum. |
| 标准范围 | 5 - 100 mIU/ml |
| 样本量 | 25 µl |
| 別名 | FSH-alpha; LSH-alpha; FSHA; Thyrotropin alpha chain; LHA; CG-alpha; GPHA1; TSHA; Chorionic gonadotrophin subunit alpha; Luteinizing hormone alpha chain; TSH-alpha; Choriogonadotropin alpha chain; GPHa; CG-ALPHA; Anterior pituitary glycoprotein hormones common subunit alpha; Follitropin alpha chain; HCG; Glycoprotein hormones alpha chain; Thyroid-stimulating hormone alpha chain; Follicle-stimulating hormone alpha chain; Lutropin alpha chain |
应用说明
| 检测时间 | 30, 10 min |
|---|
属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CGA |
| 全名 | glycoprotein hormones, alpha polypeptide |
| 背景介绍 | Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH) are intimately involved in the control of the growth and reproductive activities of the gonadal tissues, which synthesize and secrete male and female sex hormones through a negative feedback relationship. FSH is a glycoprotein secreted by the basophil cells of the anterior pituitary. Gonadotropin-releasing hormone (GnRH), produced in the hypothalamus, controls the release of FSH from the anterior pituitary. Like other glycoproteins, such as LH, TSH, and HCG, FSH consists of subunits designated as alpha and beta. Hormones of this type have alpha subunits that are very similar structurally, therefore the biological and immunological properties of each are dependent on the unique beta subunit. In the female, FSH stimulates the growth and maturation of ovarian follicles by acting directly on the receptors located on the granulosa cells; follicular steroidogenesis is promoted and LH production is stimulated. The LH produced then binds to the theca cells and stimulates steroidogenesis. Increased intraovarian estradiol production occurs as follicular maturation advances, thereupon stimulating increased FSH receptor activity and FSH follicular binding. FSH, LH, and estradiol are therefore intimately related in supporting ovarian recruitment and maturation in women. FSH levels are elevated after menopause, castration, and in premature ovarian failure. The levels of FSH may be normalized through the administration of estrogens, which demonstrate a negative feedback mechanism. Abnormal relationships between FSH and LH, between FSH and estrogen have been linked to anorexia nervosa and polycystic ovarian disease. Although there are significant exceptions ovarian failure is indicated when random FSH concentrations exceed 40 mIU/mL. The growth of the seminiferous tubules and maintenance of spermatogenesis in men are regulated by FSH. However, androgens, unlike estrogens, do not lower FSH levels, therefore demonstrating a feedback relationship only with serum LH. For reasons not fully understood, azospermic and oligospermic males usually have elevated FSH levels. Tumors of the testes generally depress serum FSH concentrations, but levels of LH are elevated, as determined by radioimmunoassay. It has been postulated that the apparent LH increase may be caused by crossreactivity with hCG-like substances secreted by tumors of the testes. High levels of FSH in men may be found in primary testicular failure and Klinefelter syndrome. Elevated concentrations are also present in cases of starvation, renal failure, hyperthyroidism, and cirrhosis. |
| 产品亮点 | Related products: FSH antibodies; FSH ELISA Kits; FSH Duos / Panels; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 研究领域 | Cell Biology and Cellular Response kit; Gene Regulation kit; Signaling Transduction kit |
检测图片 (1)
ARG80844 Human FSH ELISA Kit example of standard curve image
ARG80844 Human FSH ELISA Kit results of a typical standard run with optical density reading at 450 nm.
New Products
