Human G-CSF Receptor recombinant protein (Active) (ECD) (His-tagged, C-ter)

产品描述: HEK293 expressed, His-tagged (C-ter) Active Human G-CSF Receptor recombinant protein (ECD).
反应物种: Hu
应用: FuncSt, SDS-PAGE
靶点名称: G-CSF Receptor (ECD)
物种: Human
A.A. 序列: Glu25 - Pro621 of Human G-CSF Receptor (NP_000751.1) with 6X His tag at the C-terminus.
表达系统: HEK293
生物活性: Active
活性说明: Measured by its ability to inhibit the GCSF-induced proliferation of M-NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this ettect is typically 31.5-126 ng/ml.

CAT.NO. : ARG70289

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Size:

100 μg

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	HEK293 expressed, His-tagged (C-ter) Active Human G-CSF Receptor recombinant protein (ECD).
反应物种	Hu
应用	FuncSt, SDS-PAGE
靶点名称	G-CSF Receptor (ECD)
物种	Human
A.A. 序列	Glu25 - Pro621 of Human G-CSF Receptor (NP_000751.1) with 6X His tag at the C-terminus.
表达系统	HEK293
生物活性	Active
活性说明	Measured by its ability to inhibit the GCSF-induced proliferation of M-NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this ettect is typically 31.5-126 ng/ml.
別名	G-CSF receptor; CD114; CD antigen CD114; G-CSF-R; GCSFR; Granulocyte colony-stimulating factor receptor

属性

形式	Powder
纯化说明	0.22 µm filter sterilized. Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test.
纯度	> 95% (by SDS-PAGE)
缓冲液	PBS (pH 7.4)
复溶	Reconstitute to a concentration of 0.1 - 0.5 mg/ml in sterile distilled water.
存放说明	For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C for up to one month, at 2-8°C for up to one week. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 1441 Human CSF3R Swiss-port # Q99062 Human Granulocyte colony-stimulating factor receptor
基因名称	CSF3R
全名	colony stimulating factor 3 receptor (granulocyte)
背景介绍	The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq, Aug 2010]
生物功能	Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differientation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface. [UniProt]
细胞定位	Isoform 2: Secreted. Cell membrane; Single-pass type I membrane protein. [UniProt]
预测分子量	92 kDa
翻译后修饰	N-glycosylated. [UniProt]

检测图片 (1)

ARG70289 Human G-CSF Receptor recombinant protein (Active) (ECD) (His-tagged, C-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70289 Human G-CSF Receptor recombinant protein (Active) (ECD) (His-tagged, C-ter).

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