Human GCNT1 ELISA Kit
CAT.NO. : ARG83288
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概述
产品描述 | ARG83288 Human GCNT1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human GCNT1 in Serum, Plasma and Cell culture supernatants. |
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反应物种 | Hu |
应用 | ELISA |
特异性 | There is no detectable cross-reactivity with other relevant proteins. |
靶点名称 | GCNT1 |
偶联标记 | HRP |
偶联标记说明 | Substrate: TMB and read at 450 nm. |
灵敏度 | 15 pg/ml |
检测范围 | 62.5 pg/ml - 4,000 pg/ml |
样品类型 | Serum, Plasma and Cell culture supernatants |
精确 | Intra-Assay CV: 4.4% Inter-Assay CV: 5.6% |
別名 | NAGCT2; Core 2 GNT; G6NT; C2GNT1; Core 2-branching enzyme; Core2-GlcNAc-transferase; NACGT2; C2GNT; EC 2.4.1.102; C2GNT-L; Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase |
应用说明
检测时间 | ~ 5 hours |
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属性
形式 | 96 well |
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存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q02742 Human Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminylt |
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基因名称 | GCNT1 |
全名 | glucosaminyl (N-acetyl) transferase 1, core 2 |
背景介绍 | This gene is a member of the beta-1,6-N-acetylglucosaminyltransferase gene family. It is essential to the formation of Gal beta 1-3(GlcNAc beta 1-6)GalNAc structures and the core 2 O-glycan branch. The gene coding this enzyme was originally mapped to 9q21, but was later localized to 9q13. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] |
生物功能 | Glycosyltransferase that catalyzes the transfer of an N-acetylglucosamine moiety onto mucin-type core 1 O-glycan to form the branched mucin-type core 2 O-glycan. Mucin-type core 2 O-glycans play an important role in leukocyte extravasation as they serve as scaffolds for the display of the selectin ligand sialyl Lewis X by leukocytes. [UniProt] |
细胞定位 | Golgi apparatus membrane; Single-pass type II membrane protein. Note=Also detected in the trans-Golgi network. [UniProt] |
