Human GLB1 / beta Galactosidase ELISA Kit
Key features and details
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- 反应物种:
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- 特异性:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
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Brand:
CAT.NO. : ARG83291
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Product Details
概述
| 产品描述 | ARG83291 Human GLB1 / beta Galactosidase ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human GLB1 / beta Galactosidase in Serum, Plasma and Cell culture supernatants. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | There is no detectable cross-reactivity with other relevant proteins. |
| 靶点名称 | GLB1 / beta Galactosidase |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 15 pg/ml |
| 检测范围 | 93.7 pg/ml - 6,000 pg/ml |
| 样品类型 | Serum, Plasma and Cell culture supernatants |
| 精确 | Intra-Assay CV: 5.5% Inter-Assay CV: 5.6% |
| 別名 | ELNR1; Lactase; MPS4B; EC 3.2.1.23; Elastin receptor 1; EBP; Acid beta-galactosidase; Beta-galactosidase |
应用说明
| 检测时间 | ~ 5 hours |
|---|
属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GLB1 |
| 全名 | galactosidase, beta 1 |
| 背景介绍 | This gene encodes beta-galactosidase-1, a lysosomal enzyme that hydrolyzes the terminal beta-galactose from ganglioside substrates and other glycoconjugates. Defects in this gene are the cause of GM1-gangliosidosis and Morquio B syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008] |
| 生物功能 | Isoform 1: Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. Isoform 2 has no beta-galactosidase catalytic activity, but plays functional roles in the formation of extracellular elastic fibers (elastogenesis) and in the development of connective tissue. Seems to be identical to the elastin-binding protein (EBP), a major component of the non-integrin cell surface receptor expressed on fibroblasts, smooth muscle cells, chondroblasts, leukocytes, and certain cancer cell types. In elastin producing cells, associates with tropoelastin intracellularly and functions as a recycling molecular chaperone which facilitates the secretions of tropoelastin and its assembly into elastic fibers. [UniProt] |
| 细胞定位 | Cytoplasm; Lysosome |
| 翻译后修饰 | Disulfide bond; Glycoprotein; Zymogen |
检测图片 (1)
ARG83291 Human GLB1 / beta Galactosidase ELISA Kit standard curve image
ARG83291 Human GLB1 / beta Galactosidase ELISA Kitresults of a typical standard run with optical density reading at 450 nm.
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