Human GM-CSF recombinant protein (Active) (His-tagged, N-ter)

Key features and details

  • 产品描述: E. coli expressed, His-tagged (N-ter) Active Human GM-CSF recombinant protein
  • 应用: SDS-PAGE
  • 靶点名称: GM-CSF
  • 物种: Human
  • A.A. 序列: Ala18 - Glu144
  • 表达系统: E. coli
  • 生物活性: Active
  • 活性说明: Determined by its ability to induce TF-1 cells proliferation. The ED50 for this effect is 1 x 10^7 IU/mg.
  • 別名: GM-CSF; Granulocyte-macrophage colony-stimulating factor; CSF; GMCSF; Molgramostin; Colony-stimulating factor; Sargramostim
  • Brand:
CAT.NO. : ARG70037
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Product Details
概述
产品描述E. coli expressed, His-tagged (N-ter) Active Human GM-CSF recombinant protein
应用SDS-PAGE
靶点名称GM-CSF
物种Human
A.A. 序列Ala18 - Glu144
表达系统E. coli
生物活性Active
活性说明Determined by its ability to induce TF-1 cells proliferation. The ED50 for this effect is 1 x 10^7 IU/mg.
別名GM-CSF; Granulocyte-macrophage colony-stimulating factor; CSF; GMCSF; Molgramostin; Colony-stimulating factor; Sargramostim
属性
形式Powder
纯化说明Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test.
纯度>98% (by SDS-PAGE)
缓冲液PBS (pH 8.0)
复溶It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely.
存放说明For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
基因名称CSF2
全名colony stimulating factor 2 (granulocyte-macrophage)
背景介绍The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq, Jul 2008]
生物功能Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. [UniProt]
细胞定位Secreted. [UniProt]
产品亮点Related products:
GM-CSF antibodies; GM-CSF ELISA Kits; GM-CSF Duos / Panels; GM-CSF recombinant proteins;
Related news:
HMGB1 in inflammation
Inflammatory Cytokines
检测图片 (1)
  • ARG70037 Human GM-CSF recombinant protein (Active) (His-tagged, N-ter) SDS-PAGE image

    SDS-PAGE analysis of ARG70037 Human GM-CSF recombinant protein (Active) (His-tagged, N-ter).

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