Human HDGF ELISA Kit
Key features and details
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- 反应物种:
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- 偶联标记:
- 偶联标记说明:
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Brand:
CAT.NO. : ARG81356
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Product Details
概述
| 产品描述 | ARG81356 Human HDGF ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human HDGF in serum, plasma and cell culture supernatant. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 靶点名称 | HDGF |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | less than 30 pg/ml |
| 样品类型 | Serum, plasma and cell culture supernatant. |
| 标准范围 | 78 - 5000 pg/ml |
| 样本量 | 50 µl |
| 別名 | HMG1L2; HMG-1L2; HDGF; High mobility group protein 1-like 2; Hepatoma-derived growth factor |
应用说明
| 检测时间 | ~ 3.5 hours |
|---|
属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | HDGF |
| 全名 | hepatoma-derived growth factor |
| 背景介绍 | HDGF is a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. High levels of expression of this gene enhance the growth of many tumors. This gene was thought initially to be located on chromosome X; however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2016] |
| 生物功能 | HDGF Isoform 1: Acts as a transcriptional repressor (PubMed:17974029). Has mitogenic activity for fibroblasts (PubMed:11751870, PubMed:26845719). Heparin-binding protein (PubMed:15491618). Isoform 2: Does not have mitogenic activity for fibroblasts (PubMed:26845719). Does not bind heparin (PubMed:26845719). Isoform 3: Has mitogenic activity for fibroblasts (PubMed:26845719). Heparin-binding protein (PubMed:26845719). [UniProt] |
| 产品亮点 | Related products: HDGF antibodies; HDGF ELISA Kits; Related news: The most sensitive human HDGF ELISA kit The role of HDGF in tumor angiogenesis New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 翻译后修饰 | Sumoylated with SUMO1. Sumoylation prevents binding to chromatin. [UniProt] |
检测图片 (1)
ARG81356 Human HDGF ELISA Kit standard curve image
ARG81356 Human HDGF ELISA Kit results of a typical standard run with optical density reading at 450 nm.
参考文献
HDGF enhances VEGF-dependent angiogenesis and FGF-2 is a VEGF-independent angiogenic factor in non-small cell lung cancer.
ELISA / Human / Cell culture supernatant
HDGF supports anti-apoptosis and pro-fibrosis in pancreatic stellate cells of pancreatic cancer.
ELISA / Human
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