Human HNMT ELISA Kit

Key features and details

  • 产品描述: ARG83299 Human HNMT ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human HNMT in Serum, Plasma and Cell culture supernatants.
  • 反应物种: Hu
  • 应用: ELISA
  • 特异性: There is no detectable cross-reactivity with other relevant proteins.
  • 靶点名称: HNMT
  • 偶联标记: HRP
  • 偶联标记说明: Substrate: TMB and read at 450 nm.
  • 灵敏度: 15 pg/ml
  • 检测范围: 62.5 pg/ml - 4,000 pg/ml
  • Brand:
CAT.NO. : ARG83299
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Product Details
概述
产品描述ARG83299 Human HNMT ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human HNMT in Serum, Plasma and Cell culture supernatants.
反应物种Hu
应用ELISA
特异性There is no detectable cross-reactivity with other relevant proteins.
靶点名称HNMT
偶联标记HRP
偶联标记说明Substrate: TMB and read at 450 nm.
灵敏度15 pg/ml
检测范围62.5 pg/ml - 4,000 pg/ml
样品类型Serum, Plasma and Cell culture supernatants
精确Intra-Assay CV: 4.9%
Inter-Assay CV: 4.7%
別名HMT; Histamine N-methyltransferase; EC 2.1.1.8; HNMT-S1; HNMT-S2
应用说明
检测时间~ 5 hours
属性
形式96 well
存放说明Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 3176 Human HNMT

Swiss-port # P50135 Human Histamine N-methyltransferase

基因名称HNMT
全名histamine N-methyltransferase
背景介绍In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008]
生物功能Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine. [UniProt]
细胞定位Cytoplasm.
检测图片 (1)
  • ARG83299 Human HNMT ELISA Kit standard curve image

    ARG83299 Human HNMT ELISA Kitresults of a typical standard run with optical density reading at 450 nm.

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