Human IGFBP1 ELISA Kit
Key features and details
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- 反应物种:
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- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
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CAT.NO. : ARG82798
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Product Details
概述
| 产品描述 | ARG82798 Human IGFBP1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of IGFBP1 in Human serum. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | Cross-Reactivity: Not react with IGFBP2, 3, 4 and 5. |
| 靶点名称 | IGFBP1 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 0.5 µg/L |
| 样品类型 | Serum |
| 标准范围 | 1 - 250 µg/L |
| 样本量 | 25 µl |
| 精确 | Intra-Assay CV: 2.8% Inter-Assay CV: 6.2% |
| 別名 | IBP-1; IBP1; PP12; IGF-BP25; Insulin-like growth factor-binding protein 1; hIGFBP-1; IGFBP-1; Placental protein 12; AFBP; IGF-binding protein 1 |
应用说明
| 检测时间 | 1 hour 15 min |
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属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P08833 Human Insulin-like growth factor-binding protein 1 |
|---|---|
| 基因名称 | IGFBP1 |
| 全名 | insulin-like growth factor binding protein 1 |
| 背景介绍 | This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP N-terminal domain and a thyroglobulin type-I domain. The encoded protein, mainly expressed in the liver, circulates in the plasma and binds both insulin-like growth factors (IGFs) I and II, prolonging their half-lives and altering their interaction with cell surface receptors. This protein is important in cell migration and metabolism. Low levels of this protein may be associated with impaired glucose tolerance, vascular disease and hypertension in human patients. [provided by RefSeq, Aug 2017] |
| 生物功能 | IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 翻译后修饰 | Phosphorylated; probably by casein kinase II. Phosphorylation alters the affinity of the protein for IGFs. In amniotic fluid, the unmodified protein is the most abundant form, while mono-, bi-, tri- and tetraphosphorylated forms are present in decreasing amounts. The phosphorylation state may influence the propensity to proteolysis. [UniProt] |
检测图片 (1)
ARG82798 Human IGFBP1 ELISA Kit standard curve image
ARG82798 Human IGFBP1 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
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