Human IGFBP3 ELISA Kit
Key features and details
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CAT.NO. : ARG80494
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Product Details
概述
| 产品描述 | ARG80494 Human IGFBP3 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human IGFBP3 in serum and plasma (EDTA, heparin). |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 靶点名称 | IGFBP3 |
| 偶联标记 | HRP |
| 灵敏度 | 0.1 ng/ml |
| 样品类型 | Serum and plasma (EDTA, heparin). |
| 标准范围 | 0.4 - 30 ng/ml |
| 样本量 | 10 µl |
| 別名 | IBP-3; IBP3; Insulin-like growth factor-binding protein 3; IGFBP-3; IGF-binding protein 3; BP-53 |
应用说明
| 检测时间 | 1 h, 1 h, 30 min (RT/shaker) |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P17936 Human Insulin-like growth factor-binding protein 3 |
|---|---|
| 基因名称 | IGFBP3 |
| 全名 | insulin-like growth factor binding protein 3 |
| 背景介绍 | This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| 生物功能 | IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R. [UniProt] |
| 产品亮点 | Related products: IGFBP3 antibodies; IGFBP3 ELISA Kits; Related news: Detecting MMPs and their non-ECM substrates New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 研究领域 | Cell Biology and Cellular Response kit; Cell Death kit; Metabolism kit; Signaling Transduction kit |
| 翻译后修饰 | Phosphorylated by FAM20C in the extracellular medium. |
检测图片 (1)
ARG80494 Human IGFBP3 ELISA Kit standard curve image
ARG80494 Human IGFBP3 ELISA Kit results of a typical standard run with optical density reading at 450 - 620 nm.
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