Human IL1 beta ELISA Kit
Key features and details
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Brand:
CAT.NO. : ARG80503
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Product Details
概述
| 产品描述 | ARG80503 Human IL1 beta ELISA Kit is an Enzyme immunoassay kit for in vitro quantitative measurement of human IL1 beta in serum and plasma (EDTA). |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 靶点名称 | IL1 beta |
| 偶联标记 | HRP |
| 灵敏度 | 0.35 pg/ml |
| 样品类型 | Serum and plasma (EDTA). |
| 标准范围 | 24 - 1166 pg/ml |
| 样本量 | 200 µl |
| 別名 | Interleukin-1 beta; IL1-BETA; IL-1; IL-1 beta; Catabolin; IL1F2 |
应用说明
| 检测时间 | 2 h, 15 min (RT/shaker) |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | IL1B |
| 全名 | interleukin 1, beta |
| 背景介绍 | IL1 beta protein is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008] |
| 生物功能 | IL1 beta is a potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells (PubMed:10653850). [UniProt] |
| 产品亮点 | Related products: IL1 beta antibodies; IL1 beta ELISA Kits; IL1 beta Duos / Panels; IL1 beta recombinant proteins; Related news: HMGB1 in inflammation Inflammatory Cytokines Exploring Antiviral Immune Response RIP1 activation and pathogenesis of NASH New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 研究领域 | Cell Biology and Cellular Response kit; Immune System kit; Metabolism kit |
| 翻译后修饰 | Activation of the IL1B precursor involves a CASP1-catalyzed proteolytic cleavage. Processing and secretion are temporarily associated. |
检测图片 (1)
ARG80503 Human IL1 beta ELISA Kit standard curve image
ARG80503 Human IL1 beta ELISA Kit results of a typical standard.
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