Human IL10R subunit beta ELISA Kit
Key features and details
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- 偶联标记:
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Brand:
CAT.NO. : ARG83309
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Product Details
概述
| 产品描述 | ARG83309 Human IL10R subunit beta ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human IL10R subunit beta in Serum, Plasma and Cell culture supernatants. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | There is no detectable cross-reactivity with other relevant proteins. |
| 靶点名称 | IL10R subunit beta |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 80 pg/ml |
| 检测范围 | 156 pg/ml - 10,000 pg/ml |
| 样品类型 | Serum, Plasma and Cell culture supernatants |
| 精确 | Intra-Assay CV: 5.3% Inter-Assay CV: 7.0% |
| 別名 | Cytokine receptor family 2 member 4; CRFB4; IL-10RB; CRF2-4; Interleukin-10 receptor subunit 2; IL-10R2; D21S66; CD antigen CDw210b; IL-10R subunit 2; Interleukin-10 receptor subunit beta; D21S58; Cytokine receptor class-II member 4; CDW210B; IL-10R subunit beta; IL-10 receptor subunit beta |
应用说明
| 检测时间 | ~ 5 hours |
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属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q08334 Human Interleukin-10 receptor subunit beta |
|---|---|
| 基因名称 | IL10RB |
| 全名 | interleukin 10 receptor, beta |
| 背景介绍 | The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21. [provided by RefSeq, Jul 2008] |
| 生物功能 | Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. [UniProt] |
| 细胞定位 | Membrane; Single-pass type I membrane protein. [UniProt] |
检测图片 (1)
ARG83309 Human IL10R subunit beta ELISA Kit standard curve image
ARG83309 Human IL10R subunit beta ELISA Kitresults of a typical standard run with optical density reading at 450 nm.
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