Human IL11 ELISA Kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
- 样品类型:
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Brand:
CAT.NO. : ARG80139
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Product Details
内含物
| 货号 | 内含物名称 | 包装 | 温度 |
|---|---|---|---|
| ARG80139-001 | Antibody-coated microplate | 8 X 12 strips | 4°C. Unused strips should be sealed tightly in the air-tight pouch. |
| ARG80139-002 | Standard (Lyophilized) | 2 X 2.5 ng/vial | 4°C |
| ARG80139-003 | Standard diluent buffer | 20 ml | 4°C |
| ARG80139-004 | Antibody conjugate concentrate | 400 µl | 4°C |
| ARG80139-005 | Antibody diluent buffer | 16 ml | 4°C |
| ARG80139-006 | HRP-Streptavidin concentrate | 400 µl | 4°C (Protect from light) |
| ARG80139-007 | HRP-Streptavidin diluent buffer | 16 ml | 4°C |
| ARG80139-008 | 20X Wash buffer | 50 ml | 4°C |
| ARG80139-009 | TMB substrate | 12ml | 4°C (Protect from light) |
| ARG80139-010 | STOP solution | 12ml | 4°C |
| ARG80139-011 | Plate sealer | 4 strips | Room temperature |
概述
| 产品描述 | ARG80139 Human IL11 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human IL11 in Serum, Plasma, Cell culture supernatants. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | No significant cross-reactivity or interference with Human Cardiotrophin-1, IL-6, OSM, CNTF, LIF, G-CSF Leptin |
| 靶点名称 | IL11 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm |
| 灵敏度 | 15 pg/ml |
| 样品类型 | Serum, Plasma, Cell culture supernatants |
| 标准范围 | 31.25 - 2000 pg/ml |
| 样本量 | 100 µl |
| 精确 | CV: less than10% |
| 別名 | Oprelvekin; Interleukin-11; AGIF; Adipogenesis inhibitory factor; IL-11 |
应用说明
| 检测时间 | 4 hours |
|---|
属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | IL11 |
| 全名 | interleukin 11 |
| 背景介绍 | The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2012] |
| 生物功能 | Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. [UniProt] |
| 产品亮点 | Related products: IL11 antibodies; IL11 ELISA Kits; Related news: LKB1 deficiency in T cells promotes gut tumors New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 研究领域 | Cancer kit; Cell Biology and Cellular Response kit; Developmental Biology kit; Immune System kit |
检测图片 (1)
ARG80139 Human IL11 ELISA Kit standard curve image
ARG80139 Human IL11 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
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