Human IL32 recombinant protein (Active) (His-tagged, C-ter)
Key features and details
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Brand:
CAT.NO. : ARG70076
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Product Details
概述
| 产品描述 | E. coli expressed, His-tagged (C-ter) Active Human IL32 recombinant protein |
|---|---|
| 应用 | SDS-PAGE |
| 靶点名称 | IL32 |
| 物种 | Human |
| A.A. 序列 | Met1 - Lys131 |
| 表达系统 | E. coli |
| 生物活性 | Active |
| 活性说明 | Determined by its ability to induce TNF alpha secretion in RAW264.7 cells. The ED50 for this effect is |
| 別名 | IL-32gamma; IL-32beta; IL-32delta; Interleukin-32; TAIFa; TAIFc; TAIFb; NK4; TAIFd; IL-32; TAIF; Natural killer cells protein 4; Tumor necrosis factor alpha-inducing factor; IL-32alpha |
属性
| 形式 | Powder |
|---|---|
| 纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | >98% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 8.0) |
| 复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | IL32 |
|---|---|
| 全名 | interleukin 32 |
| 背景介绍 | This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| 生物功能 | Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF-alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
检测图片 (1)
ARG70076 Human IL32 recombinant protein (Active) (His-tagged, C-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70076 Human IL32 recombinant protein (Active) (His-tagged, C-ter).
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