Human IL36RN ELISA Kit
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CAT.NO. : ARG83444
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Product Details
概述
| 产品描述 | ARG83444 Human IL36RN ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human IL36RN in Serum, plasma and cell culture supernatants., Tissue Homogenates |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 靶点名称 | IL36RN |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 50 pg/ml |
| 样品类型 | Serum, plasma and cell culture supernatants., Tissue Homogenates |
| 标准范围 | 93.7 - 6000 pg/ml |
| 样本量 | 100 µl |
| 精确 | Intra-Assay CV: less than 10% Inter-Assay CV: less than 10% |
| 別名 | IL36RN; Interleukin 36 Receptor Antagonist; IL1HY1; IL1RP3; FIL1D; IL1L1; Interleukin-1 Receptor Antagonist Homolog 1; Interleukin-1 HY1; FIL1(DELTA); IL-1F5; IL36RA; IL1F5; FIL1; Interleukin-36 Receptor Antagonist Protein; Interleukin 1 Family, Member 5 (Delta); Interleukin-1-Like Protein 1; IL-1 Related Protein 3; IL-1ra Homolog 1; MGC29840; IL-36Ra; IL-1F5 (IL-1HY1, FIL1-Delta, IL-1RP3, IL-1L1, IL-1-Delta); IL1F5 (Canonical Product IL-1F5a); Family Of Interleukin 1-Delta; Interleukin-1 Family Member 5; IL-1-Related Protein 3; Interleukin-1 Delta; FIL1 Delta; IL-1 Delta; PSORS14; IL-1RP3; IL-1HY1; IL-1L1; PSORP |
应用说明
| 检测时间 | 3.5 hours |
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属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 4°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q9UBH0 Human Interleukin-36 receptor antagonist protein |
|---|---|
| 基因名称 | IL36RN |
| 全名 | Interleukin 36 Receptor Antagonist |
| 背景介绍 | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine was shown to specifically inhibit the activation of NF-kappaB induced by interleukin 1 family, member 6 (IL1F6). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding the same protein have been reported. |
| 生物功能 | Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR. |
| 细胞定位 | Cytoplasm, Secreted |
| 翻译后修饰 | Disulfide bond |
检测图片 (1)
ARG83444 Human IL36RN ELISA Kit standard curve image
ARG83444 Human IL36RN ELISA Kitresults of a typical standard run with optical density reading at 450 nm.
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