Human Klotho ELISA Kit
Key features and details
- Specificity:40 pg/ml
- Detection Range: 78 pg/ml - 5000 pg/ml
- Sample Types: Serum, plasma or cell culture supernatants.
- Species:Human
- Detection Method: Colorimetric
- Target:Klotho
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Brand:
CAT.NO. : ARE6623
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Size:
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Product Details
Background
KLOTHO is the systemic anti-aging hormone within the glycosidase1 superfamily. It encodes a type I membrane protein that is abundant in the kidney and brain. In mice, a deficiency in KLOTHO expression leads to various systemic phenotypes resembling human aging such as arteriosclerosis, osteoporosis, and skin atrophy together with growth retardation, short life-span and infertility. Transgenic mice overexpressing KLOTHO have an extended life span by inhibiting insulin/IGF1 signaling. KLOTHO is involved in the regulation of calcium/phosphorus homeostasis by inhibiting the synthesis of active vitamin D and identified as a potential tumor suppressor.
Overview
|
Product Description |
Sandwich ELISA for quantitative detection of Human Klotho concentrations. |
|
Specificity |
40 pg/ml |
|
Gene Name |
KL |
|
Alternative Name |
Klotho |
|
Human Gene ID |
9365 |
|
Human Protein ID |
Q9UEF7 |
|
Detection Method |
Colorimetric |
|
Detection Range |
78 pg/ml - 5000 pg/ml |
Data
Representative Standard Curve
Storage
Shipped and store at 4°C.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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