Human LPL / Lipoprotein Lipase ELISA Kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
- 检测范围:
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Brand:
CAT.NO. : ARG83321
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Product Details
概述
| 产品描述 | ARG83321 Human LPL / Lipoprotein Lipase ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human LPL / Lipoprotein Lipase in Serum, Plasma and Cell culture supernatants. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | There is no detectable cross-reactivity with other relevant proteins. |
| 靶点名称 | LPL / Lipoprotein Lipase |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 45 pg/ml |
| 检测范围 | 78 pg/ml - 5,000 pg/ml |
| 样品类型 | Serum, Plasma and Cell culture supernatants |
| 精确 | Intra-Assay CV: 6.1% Inter-Assay CV: 5.7% |
| 別名 | EC 3.1.1.34; LPL; Lipoprotein lipase; LIPD; HDLCQ11 |
应用说明
| 检测时间 | ~ 5 hours |
|---|
属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | LPL |
| 全名 | lipoprotein lipase |
| 背景介绍 | LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. [provided by RefSeq, Jul 2008] |
| 生物功能 | The primary function of this lipase is the hydrolysis of triglycerides of circulating chylomicrons and very low density lipoproteins (VLDL). Binding to heparin sulfate proteogylcans at the cell surface is vital to the function. The apolipoprotein, APOC2, acts as a coactivator of LPL activity in the presence of lipids on the luminal surface of vascular endothelium (By similarity). [UniProt] |
| 细胞定位 | Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Note=Locates to the plasma membrane of microvilli of hepatocytes with triacyl-glycerol-rich lipoproteins (TRL). Some of the bound LPL is then internalized and located inside non-coated endocytic vesicles (By similarity). [UniProt] |
| 翻译后修饰 | Tyrosine nitration after lipopolysaccharide (LPS) challenge down-regulates the lipase activity. [UniProt] |
检测图片 (1)
ARG83321 Human LPL / Lipoprotein Lipase ELISA Kit standard curve image
ARG83321 Human LPL / Lipoprotein Lipase ELISA Kitresults of a typical standard run with optical density reading at 450 nm.
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