Human MMP7 recombinant protein (His-tagged, C-ter)
Key features and details
- 产品描述:
- 应用:
- 靶点名称:
- 物种:
- A.A. 序列:
- 表达系统:
- Protein Full name:
- 別名:
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Brand:
CAT.NO. : ARG70452
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Product Details
概述
| 产品描述 | E. coli expressed, His-tagged (C-ter) Human MMP7 recombinant protein |
|---|---|
| 应用 | SDS-PAGE |
| 靶点名称 | MMP7 |
| 物种 | Human |
| A.A. 序列 | Tyr95 - Lys276 |
| 表达系统 | E. coli |
| Protein Full name | Matrilysin |
| 別名 | MMP7; Matrix Metallopeptidase 7; Matrilysin; PUMP-1; MPSL1; Matrix Metalloproteinase 7 (Matrilysin, Uterine); Matrix Metalloproteinase-7; Uterine Metalloproteinase; Pump-1 Protease; Matrin; MMP-7 |
属性
| 形式 | Powder |
|---|---|
| 纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | >98% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 8.0) |
| 复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | MMP7 |
|---|---|
| 全名 | Matrix Metallopeptidase 7 |
| 背景介绍 | This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers. |
| 生物功能 | Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase. |
| 细胞定位 | Extracellular matrix, Secreted |
| 翻译后修饰 | Zymogen |
检测图片 (1)
ARG70452 Human MMP7 recombinant protein (His-tagged, C-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70452 Human MMP7 recombinant protein (His-tagged, C-ter)
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