Human MMP8 Assay Kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 靶点名称:
- 偶联标记说明:
- 灵敏度:
- 检测范围:
- 样品类型:
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Brand:
CAT.NO. : ARG82630
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Product Details
概述
| 产品描述 | ARG82630 Human MMP8 Assay Kit is a detection kit for the quantification of Human MMP8 in serum, plasma, cell culture supernatants, urine, saliva and tissue homogenates. |
|---|---|
| 反应物种 | Hu |
| 应用 | FuncSt |
| 特异性 | Measures endogenous active MMP8 (naturally occurring) or total active MMP8 (following activation with APMA). |
| 靶点名称 | MMP8 |
| 偶联标记说明 | Read at 405 nm. |
| 灵敏度 | 100 pg/ml for 2 hours incubation 24 pg/ml for 6 hours incubation 4 pg/ml for 24 hours incubation |
| 检测范围 | 10 - 24000 pg/ml |
| 样品类型 | Serum, plasma, cell culture supernatants, urine, saliva and tissue homogenates. |
| 样本量 | 100 µl |
| 別名 | HNC; PMNL collagenase; MMP-8; PMNL-CL; CLG1; Neutrophil collagenase; Matrix metalloproteinase-8; EC 3.4.24.34 |
应用说明
| 检测时间 | Overnight |
|---|
属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at -20°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MMP8 |
| 全名 | matrix metallopeptidase 8 |
| 背景介绍 | This gene encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] |
| 生物功能 | Can degrade fibrillar type I, II, and III collagens. [UniProt] |
| 细胞定位 | Cytoplasmic granule. Secreted, extracellular space, extracellular matrix. Note=Stored in intracellular granules. [UniProt] |
检测图片 (3)
ARG82630 Human MMP8 Assay Kit typical data demonstration image
ARG82630 Human MMP8 Assay Kit results of a typical data with optical density reading at 405 nm (after 2 hours incubation).
ARG82630 Human MMP8 Assay Kit typical data demonstration image
ARG82630 Human MMP8 Assay Kit results of a typical data with optical density reading at 405 nm (after 6 hours incubation).
ARG82630 Human MMP8 Assay Kit typical data demonstration image
ARG82630 Human MMP8 Assay Kit results of a typical data with optical density reading at 405 nm (after 24 hours incubation).
参考文献
Adipose-derived stem cells enriched with therapeutic mRNA TGF-β3 and IL-10 synergistically promote scar-less wound healing in preclinical models
ELISA / Human / Culture supernatant
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