Human Neuroserpin ELISA Kit

Key features and details

  • 产品描述: ARG80186 Human Neuroserpin ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Neuroserpin in Serum, Plasma, Cell culture supernatants.
  • 反应物种: Hu
  • 应用: ELISA
  • 特异性: No significant cross-reactivity or interference with Human IL-2,3,4,5,6,7,9,10,12, IFN- gamma, TNF- alpha;mouse neuroserpin
  • 靶点名称: Neuroserpin
  • 偶联标记: HRP
  • 偶联标记说明: Substrate: TMB and read at 450 nm
  • 灵敏度: 30 pg/ml
  • 样品类型: Serum, Plasma, Cell culture supernatants
  • Brand:
CAT.NO. : ARG80186
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Product Details
内含物
货号内含物名称包装温度
ARG80186-001Antibody-coated microplate8 X 12 strips 4°C. Unused strips should be sealed tightly in the air-tight pouch.
ARG80186-002Standard (Lyophilized)3 X 4 ng/vial 4°C
ARG80186-003Standard diluent buffer20 ml 4°C
ARG80186-004Antibody conjugate concentrate400 µl 4°C
ARG80186-005Antibody diluent buffer16 ml 4°C
ARG80186-006HRP-Streptavidin concentrate400 µl 4°C (Protect from light)
ARG80186-007HRP-Streptavidin diluent buffer16 ml 4°C
ARG80186-00820X Wash buffer50 ml 4°C
ARG80186-009TMB substrate12ml 4°C (Protect from light)
ARG80186-010STOP solution12ml 4°C
ARG80186-011Plate sealer4 strips Room temperature
概述
产品描述ARG80186 Human Neuroserpin ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Neuroserpin in Serum, Plasma, Cell culture supernatants.
反应物种Hu
应用ELISA
特异性No significant cross-reactivity or interference with Human IL-2,3,4,5,6,7,9,10,12, IFN- gamma, TNF- alpha;mouse neuroserpin
靶点名称Neuroserpin
偶联标记HRP
偶联标记说明Substrate: TMB and read at 450 nm
灵敏度30 pg/ml
样品类型Serum, Plasma, Cell culture supernatants
标准范围62.5 - 4000 pg/ml
样本量100 µl
精确CV: less than10%
別名Peptidase inhibitor 12; neuroserpin; Neuroserpin; Serpin I1; PI12; PI-12
应用说明
检测时间4 hours
属性
形式96 well
存放说明Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 5274 Human SERPINI1

Swiss-port # Q99574 Human Neuroserpin

基因名称SERPINI1
全名serpin peptidase inhibitor, clade I (neuroserpin), member 1
背景介绍Neuroserpin is an inhibitory serpin that is expressed predominantly in central nervous system. Although the physiological target of neuroserpin is still unclear, cumulative evidence suggest that it plays an important role in controlling proteolytic degradation of extracellular matrix (ECM) during synaptogenesis and the subsequent development of neuronal plasticity. In the adult brain, neuroserpin is secreted from the growth cones of neurons in areas where synaptic changes are associated with learning and memory, i.e. cerebral cortex, hippocampus, and amygdala. The neuroprotective role of neuroserpin has been demonstrated in transgenic mice lacking neuroserpin expression. The deficiency of neuroserpin in these mice was associated with motor neuron disease characterized by axonal degradation. In humans, defects in neuroserpin, caused by point mutations in the neuroserpin gene, underlie a hereditary disorder called the familial encephalopathy with neuroserpin inclusion bodies (FENIB). Recombinant human neuroserpin is a 44.6 kDa non-glycosylated protein containing 394 amino-acid residues.
产品亮点Related products:
Neuroserpin antibodies; Neuroserpin ELISA Kits;
New ELISA data calculation tool:
Simplify the ELISA analysis by GainData
研究领域Neuroscience kit
检测图片 (1)
  • ARG80186 Human Neuroserpin ELISA Kit standard curve image

    ARG80186 Human Neuroserpin ELISA Kit results of a typical standard run with optical density reading at 450 nm.

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