Human Neutrophil Elastase / alpha 1 Proteinase Inhibitor Complex ELISA Kit
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CAT.NO. : ARG80507
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Product Details
概述
| 产品描述 | ARG80507 Human Neutrophil Elastase / alpha 1 Proteinase Inhibitor Complex ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Neutrophil Elastase / alpha 1 Proteinase Inhibitor Complex in plasma (EDTA, citrate), seminal plasma, exudate, BALF and CSF. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 靶点名称 | Neutrophil Elastase / alpha 1 Proteinase Inhibitor Complex |
| 偶联标记 | HRP |
| 灵敏度 | 0.2 ng/ml |
| 样品类型 | Plasma (EDTA, citrate), seminal plasma, exudate, BALF and CSF. |
| 标准范围 | 15.6 - 1000 ng/ml |
| 样本量 | 100 µl |
| 別名 | Neutrophil elastase; HNE; EC 3.4.21.37; Medullasin; NE; ELA2; GE; Bone marrow serine protease; SCN1; PMN-E; Human leukocyte elastase; HLE; Elastase-2; PMN elastase |
应用说明
| 检测时间 | 1 h, 1 h (RT/shaking), 20 min (RT/dark) |
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属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ELANE |
| 全名 | elastase, neutrophil expressed |
| 背景介绍 | Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins. The product of this gene hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix following the protein's release from activated neutrophils. The enzyme may play a role in degenerative and inflammatory diseases by its proteolysis of collagen-IV and elastin of the extracellular matrix. This protein degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is clustered with other serine protease gene family members, azurocidin 1 and proteinase 3 genes, at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. [provided by RefSeq, May 2009] |
| 生物功能 | Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis. [UniProt] |
| 产品亮点 | Related products: Neutrophil Elastase antibodies; Neutrophil Elastase ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 研究领域 | Microbiology and Infectious Disease kit; Signaling Transduction kit |
检测图片 (1)
ARG80507 Human Neutrophil Elastase / alpha 1 Proteinase Inhibitor Complex ELISA Kit standard curve image
ARG80507 Human Neutrophil Elastase / alpha 1 Proteinase Inhibitor Complex ELISA Kit results of a typical standard.
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