Human PNP / Purine nucleoside phosphorylase ELISA Kit
Key features and details
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- 反应物种:
- 应用:
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- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
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CAT.NO. : ARG83344
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Product Details
概述
| 产品描述 | ARG83344 Human PNP / Purine nucleoside phosphorylase ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human PNP / Purine nucleoside phosphorylase in serum, plasma and cell culture supernatants. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | There is no detectable cross-reactivity with other relevant proteins. |
| 靶点名称 | PNP / Purine nucleoside phosphorylase |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 15 pg/ml |
| 检测范围 | 31.2 pg/ml - 2000 pg/ml |
| 样品类型 | Serum, Plasma and Cell culture supernatants. |
| 別名 | EC 2.4.2.1; Purine nucleoside phosphorylase; Inosine-guanosine phosphorylase; PNP; PRO1837; Inosine phosphorylase; PUNP; NP |
应用说明
| 检测时间 | ~ 5 hours |
|---|
属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PNP |
| 全名 | purine nucleoside phosphorylase |
| 背景介绍 | This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2. [provided by RefSeq, Jul 2008] |
| 生物功能 | The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. [UniProt] |
| 细胞定位 | Cytoplasm, cytoskeleton. Cytoplasm |
| 研究领域 | Neuroscience antibody |
检测图片 (1)
ARG83344 Human PNP / Purine nucleoside phosphorylase ELISA Kit standard curve image
ARG83344 Human PNP / Purine nucleoside phosphorylase ELISA Kitresults of a typical standard run with optical density reading at 450 nm.
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