Human Prolactin ELISA Kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
- 样品类型:
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Brand:
CAT.NO. : ARG80852
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Product Details
概述
| 产品描述 | ARG80852 Human Prolactin ELISA Kit is an enzyme immunoassay kit for the quantification of Prolactin in serum. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | This ELISA kit is no cross-reactivity with hCG, TSH, LH, FSH, or hGH. |
| 靶点名称 | Prolactin |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm |
| 灵敏度 | 0.35 ng/ml |
| 样品类型 | Serum. |
| 标准范围 | 5 - 200 ng/ml |
| 样本量 | 25 µl |
| 別名 | Prolactin; PRL |
应用说明
| 检测时间 | 30, 10 min (RT) |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PRL |
| 全名 | prolactin |
| 背景介绍 | Human prolactin (lactogenic hormone) is secreted from the anterior pituitary gland in both men and women. Human prolactin is a single chain polypeptide hormone with a molecular weight of approximately 23.000 daltons. The release and synthesis of prolactin is under neuroendocrinal control, primarily through Prolactin Releasing Factor and Prolactin Inhibiting Factor. Women normally have slightly higher basal prolactin levels than men; apparently, there is an estrogen- related rise at puberty and a corresponding decrease at menopause. The primary functions of prolactin are to initiate breast development and to maintain lactation. Prolactin also suppresses gonadal function. During pregnancy, prolactin levels increase progressively to between 10 and 20 times normal values, declining to non-pregnant levels by 3-4 weeks post- partum. Breast feeding mothers maintain high levels of prolactin, and it may take several months for serum concentrations to return to non-pregnant levels. The determination of prolactin concentration is helpful in diagnosing hypothalamic- pituitary disorders. Microadenomas (small pituitary tumors) may cause hyperprolactinemia, which is sometimes associated with male impotence. High prolactin levels are commonly associated with galactorrhea and amenorrhea. Prolactin concentrations have been shown to be increased by estrogens, thyrotropin- releasing hormone (TRH), and several drugs affecting dopaminergic mechanisms. Prolactin levels are elevated in renal disease and hypothyroidism, and in some situations of stress, exercise, and hypoglycemia. Additionally, the release of prolactin is episodic and demonstrates diurnal variation. Mildly elevated prolactin concentrations should be evaluated taking these considerations into account. Prolactin concentrations may also be increased by drugs such as chloropromazine and reserpine, and may be lowered by bromocyptine and L-dopa. |
| 产品亮点 | Related products: Prolactin antibodies; Prolactin ELISA Kits; Prolactin Duos / Panels; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 研究领域 | Signaling Transduction kit |
检测图片 (1)
ARG80852 Human Prolactin ELISA Kit example of standard curve image
ARG80852 Human Prolactin ELISA Kit results of a typical standard run with optical density reading at 450 nm.
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