Human Prolactin Receptor ELISA Kit
Key features and details
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- 偶联标记:
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Brand:
CAT.NO. : ARG82588
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Product Details
概述
| 产品描述 | ARG82588 Human Prolactin Receptor ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Prolactin Receptor in serum, plasma and cell culture supernatants. |
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| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | This kit could assay both natural and recombinant Human Prolactin Receptor. No significant cross-reactivity or interference was observed in the following samples: Human: IFN gamma, IL1 beta, IL2, IL4, IL5, IL6, IL8, IL10, IL12, IL17A, IL18, IL21, IL22, IL23, MCP1, TGF beta 1, TNF alpha and VEGF. Mouse: GM-CSF, IFN gamma, IL1 beta, IL2, IL4, IL6, IL10, IL17A and TNF alpha. Rat: IFN gamma, IL1 beta, IL4, IL6, IL10 and TNF alpha. |
| 靶点名称 | Prolactin Receptor |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 7.8 pg/ml |
| 样品类型 | Serum, plasma and cell culture supernatants. |
| 标准范围 | 15.6 - 1000 pg/ml |
| 样本量 | 50 - 100 µl |
| 精确 | Intra-Assay CV: 2.4% Inter-Assay CV: 2.5% |
| 別名 | MFAB; hPRLrI; PRL-R; Prolactin receptor; HPRL |
应用说明
| 检测时间 | ~ 3.5 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PRLR |
| 全名 | prolactin receptor |
| 背景介绍 | This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011] |
| 生物功能 | This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling. [UniProt] |
| 细胞定位 | Membrane; Single-pass type I membrane protein. Isoform 7: Secreted. [UniProt] |
| 产品亮点 | Related products: Prolactin Receptor antibodies; Prolactin Receptor ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
检测图片 (1)
ARG82588 Human Prolactin Receptor ELISA Kit standard curve image
ARG82588 Human Prolactin Receptor ELISA Kit results of a typical standard run with optical density reading at 450 nm.
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