Human Siglec 15 recombinant protein (Active) (ECD) (Fc-His-tagged, C-ter)
CAT.NO. : ARG70326
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概述
| 产品描述 | HEK293 expressed, Fc-His-tagged (C-ter) Active Human Siglec 15 recombinant protein (ECD). |
|---|---|
| 反应物种 | Hu |
| 应用 | FuncSt, SDS-PAGE |
| 靶点名称 | Siglec 15 (ECD) |
| 物种 | Human |
| A.A. 序列 | Phe20 - Thr263 of Human Siglec 15 (NP_998767.1) with an Fc-6X His tag at the C-terminus. |
| 表达系统 | HEK293 |
| 生物活性 | Active |
| 活性说明 | Measured by its ability to inhibit Anti-CD3-induced proliferation of Jurkat cells. The ED50 for this effect is 1.8-7.2 µg/ml. |
| 別名 | HsT1361; CD33 antigen-like 3; SIGLEC-15; CD33L3; Sialic acid-binding Ig-like lectin 15; Siglec-15 |
属性
| 形式 | Powder |
|---|---|
| 纯化说明 | 0.22 µm filter sterilized. Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) and 300 mM NaCl. |
| 复溶 | Reconstitute to a concentration of 0.1 - 0.5 mg/ml in sterile distilled water. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C for up to one month, at 2-8°C for up to one week. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q6ZMC9 Human Sialic acid-binding Ig-like lectin 15 |
|---|---|
| 基因名称 | SIGLEC15 |
| 全名 | sialic acid binding Ig-like lectin 15 |
| 生物功能 | Binds sialylated glycoproteins. [UniProt] |
| 细胞定位 | Membrane; Single-pass type I membrane protein. [UniProt] |
| 预测分子量 | 36 kDa |
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