Human Siglec 15 recombinant protein (Active) (ECD) (His-tagged, C-ter)

Key features and details

  • 产品描述: HEK293 expressed, His-tagged (C-ter) Active Human Siglec 15 recombinant protein (ECD).
  • 反应物种: Hu
  • 应用: FuncSt, SDS-PAGE
  • 靶点名称: Siglec 15 (ECD)
  • 物种: Human
  • A.A. 序列: Phe20 - Thr263 of Human Siglec 15 (NP_998767.1) with 6X His tag at the C-terminus.
  • 表达系统: HEK293
  • 生物活性: Active
  • 活性说明: Measured by its ability to inhibit Anti-CD3-induced proliferation of Jurkat cells. The ED50 for this effect is 4.99-19.98 µg/ml.
  • Brand:
CAT.NO. : ARG70342
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Product Details
概述
产品描述HEK293 expressed, His-tagged (C-ter) Active Human Siglec 15 recombinant protein (ECD).
反应物种Hu
应用FuncSt, SDS-PAGE
靶点名称Siglec 15 (ECD)
物种Human
A.A. 序列Phe20 - Thr263 of Human Siglec 15 (NP_998767.1) with 6X His tag at the C-terminus.
表达系统HEK293
生物活性Active
活性说明Measured by its ability to inhibit Anti-CD3-induced proliferation of Jurkat cells. The ED50 for this effect is 4.99-19.98 µg/ml.
別名HsT1361; CD33 antigen-like 3; SIGLEC-15; CD33L3; Sialic acid-binding Ig-like lectin 15; Siglec-15
属性
形式Powder
纯化说明0.22 µm filter sterilized. Endotoxin level is less than 1.0 EU/µg of the protein, as determined by the LAL test.
纯度> 95% (by SDS-PAGE)
缓冲液PBS (pH 7.4) and 300 mM NaCl.
复溶Reconstitute to a concentration of 0.1 - 0.5 mg/ml in sterile distilled water.
存放说明For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C for up to one month, at 2-8°C for up to one week. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 284266 Human SIGLEC15

Swiss-port # Q6ZMC9 Human Sialic acid-binding Ig-like lectin 15

基因名称SIGLEC15
全名sialic acid binding Ig-like lectin 15
生物功能Binds sialylated glycoproteins. [UniProt]
细胞定位Membrane; Single-pass type I membrane protein. [UniProt]
预测分子量36 kDa
检测图片 (1)
  • ARG70342 Human Siglec 15 recombinant protein (Active) (ECD) (His-tagged, C-ter) SDS-PAGE image

    SDS-PAGE analysis of ARG70342 Human Siglec 15 recombinant protein (Active) (ECD) (His-tagged, C-ter).

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