Human TIE1 ELISA Kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
- 样品类型:
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Brand:
CAT.NO. : ARG82596
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Product Details
概述
| 产品描述 | ARG82596 Human TIE1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human TIE1 in serum, plasma and cell culture supernatants. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | This kit could assay both natural and recombinant Human TIE1. No significant cross-reactivity or interference was observed in the following samples: Human: IFN gamma, IL1 beta, IL2, IL4, IL5, IL6, IL8, IL10, IL12, IL17A, IL18, IL21, IL22, IL23, MCP1, TGF beta 1, TNF alpha and VEGF. Mouse: GM-CSF, IFN gamma, IL1 beta, IL2, IL4, IL6, IL10, IL17A and TNF alpha. Rat: IFN gamma, IL1 beta, IL4, IL6, IL10 and TNF alpha. |
| 靶点名称 | TIE1 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 0.16 ng/ml |
| 样品类型 | Serum, plasma and cell culture supernatants. |
| 标准范围 | 0.31 - 20 ng/ml |
| 样本量 | 20 µl |
| 精确 | Intra-Assay CV: 3.6% Inter-Assay CV: 2.5% |
| 別名 | TIE; Tyrosine-protein kinase receptor Tie-1; JTK14; EC 2.7.10.1 |
应用说明
| 检测时间 | ~ 2.5 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P35590 Human Tyrosine-protein kinase receptor Tie-1 |
|---|---|
| 基因名称 | TIE1 |
| 全名 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 |
| 背景介绍 | This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011] |
| 生物功能 | Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis. [UniProt] |
| 细胞定位 | Cell membrane; Single-pass type I membrane protein. [UniProt] |
| 产品亮点 | Related products: TIE1 antibodies; TIE1 ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 翻译后修饰 | Phosphorylated on tyrosine residues in response to ANGPT1, most likely by TEK/TIE2. [UniProt] |
检测图片 (1)
ARG82596 Human TIE1 ELISA Kit standard curve image
ARG82596 Human TIE1 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
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