Human TNFSF18 / GITRL ELISA Kit
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CAT.NO. : ARG82052
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Product Details
概述
| 产品描述 | Human TNFSF18 / GITRL ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human TNFSF18 / GITRL in serum, plasma and cell culture supernatants. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 靶点名称 | TNFSF18 / GITRL |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 62.5 pg/ml |
| 样品类型 | Serum, plasma and cell culture supernatants. |
| 标准范围 | 125 - 8000 pg/ml |
| 样本量 | 100 µl |
| 別名 | TL6; AITRL; Glucocorticoid-induced TNF-related ligand; Tumor necrosis factor ligand superfamily member 18; hGITRL; Activation-inducible TNF-related ligand; GITRL |
应用说明
| 检测时间 | 4.5 hours |
|---|
属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q9UNG2 Human Tumor necrosis factor ligand superfamily member 18 |
|---|---|
| 基因名称 | TNFSF18 |
| 全名 | tumor necrosis factor (ligand) superfamily, member 18 |
| 背景介绍 | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq, Jul 2008] |
| 生物功能 | Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1. Promotes leukocyte adhesion to endothelial cells. Regulates migration of monocytes from the splenic reservoir to sites of inflammation (By similarity). [UniProt] |
| 细胞定位 | Cell membrane; Single-pass type II membrane protein. [UniProt] |
| 产品亮点 | Related products: TNFSF antibodies; TNFSF ELISA Kits; TNFSF Duos / Panels; TNFSF recombinant proteins; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
检测图片 (1)
ARG82052 Human TNFSF18 / GITRL ELISA Kit standard curve image
ARG82052 Human TNFSF18 / GITRL ELISA Kit results of a typical standard run with optical density reading at 450 nm.
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