IDO1 Rabbit Monoclonal Antibody(ARM625)
Key features and details
- Target:
- Clone ID:
- Host:
- Species Cross-reactivity:
- Applications:
- Dilution:
- Clonality:
-
Brand:
CAT.NO. : ARM6916
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Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
Indoleamine 2,3-dioxygenase 1 (IDO1) is a cytoplasmic enzyme encoded by the INDO gene on human chromosome 8p22. IDO1 modulates levels of the amino acid tryptophan, which is vital for cell growth, but is also involved in immune evasion and tumor outgrowth. Blocking the IDO1 pathway may be a potential target for immuno and cancer therapy. IDO1 expressions have been found in endometrial, cervical carcinomas, renal cell carcinomas, non-small cell lung carcinomas, and colorectal carcinomas.
Application
|
Application |
Dilution Ratio |
|
IHC |
1:50 - 1:200 |
Overview
|
Molecular Weight |
45,326 Da |
|
Chromosome Location |
Chromosome: 8; NC_000008.10 (39771328..39786309). Location: 8p12-p11 |
|
3D Structure |
ModBase 3D Structure for P14902 |
|
Isotype |
IgG |
|
Host |
Rabbit |
|
Species Reactivity |
Human |
|
Purity/Purification |
Purified |
|
Form/Format |
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
|
Immunogen |
Recombinant Protein |
Data
Immunohistochemical staining of human tonsil tissue using IDO1 Rabbit Monoclonal Antibody (ARM625).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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