IMP3 Rabbit Monoclonal Antibody(ARM510)
Key features and details
- Target:
- Clone ID:
- Host Species:
- Species Cross-reactivity:
- Applications:
- Dilution:
- Clonality:
-
Brand:
CAT.NO. : ARM6800
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
Insulin-like growth factor 2 mRNA-binding protein 3 (IMP3), is a regulator of targets such as insulin-like growth factor-2 and β-actin. The protein is localized mainly in the nucleolus, and plays a critical role in early embryogenesis as it helps mediate the development of the intestine, thymus, pancreas, and kidneys. IMP3 has been reported as a potential aid in the classification of non-small cell lung carcinomas and pancreatic adenocarcinomas, and studies have shown IMP3 to be correlated with increased tumour aggressiveness and reduced overall survival. IMP3 has also been clinically linked to a number of other cancers including adenocarcinomas of the uterine cervix and esophagus, as well as triple negative breast cancer, endometrial and urothelial carcinomas, renal cell and Merkel cell carcinomas, malignant melanoma, and neuroendocrine carcinoma of the lung.
Application
|
Application |
Dilution Ratio |
|
IHC |
1:50 - 1:200 |
Overview
|
Molecular Weight |
21,850 Da |
|
OMIM |
612980 |
|
3D Structure |
ModBase 3D Structure for Q9NV31 |
|
Isotype |
IgG |
|
Host |
Rabbit |
|
Species Reactivity |
Human |
|
Purity/Purification |
Purified |
|
Form/Format |
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
|
Immunogen |
Recombinant Protein |
Data
Immunohistochemical staining of human pancreatic cancer tissue using IMP3 Rabbit Monoclonal Antibody (ARM510).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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