INSL3 Rabbit Polyclonal Antibody

Key features and details

Reactivity:Human, Mouse, Rat
Application:IHC, ELISA, IF/ICC
Host:Rabbit
Clonality:polyclonal
Target:INSL3

Brand:

CAT.NO. : ARA6420

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Size:

100μL 50μL

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Product Details

Background

This gene encodes a member of the insulin-like hormone superfamily. The encoded protein is mainly produced in gonadal tissues. Studies of the mouse counterpart suggest that this gene may be involved in the development of urogenital tract and female fertility. This protein may also act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent. Mutations in this gene may lead to cryptorchidism. Alternate splicing results in multiple transcript variants.

Application

Application	Dilution Ratio
IHC	1:50 - 1:200
ELISA	1:10,000 - 1:20,000
IF/ICC	1:50 - 1:200

Overview

Composition	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity	The antibody detects endogenous INSL3.
Purification Process	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration	1 mg/mL
Modification	Unmodified
Clonality	Polyclonal
Isotype	IgG
Immunogen	Synthetic peptide from human protein at AA range: 10-50
Gene Symbol	INSL3, RLF, RLNL
Protein Name	Insulin-like 3 (Leydig insulin-like peptide) (Ley-I-L) (Relaxin-like factor) [Cleaved into: Insulin-like 3 B chain; Insulin-like 3 A chain]
Alternative Names	Insulin-like 3; Leydig insulin-like peptide; Ley-I-L
Gene ID (Human)	3640
SwissProt ID (Human)	P51460
SwissProt ID (Mouse)	O09107
Subcellular Location	Secreted.
Tissue Expression	Expressed in prenatal and postnatal Leydig cells. Found as well in the corpus luteum, trophoblast, fetal membranes and breast.