Integrin α6 (14V4) Rabbit Monoclonal Antibody(ARA984)

Key features and details

Reactivity:Human, Mouse, Rat
Application:WB, IHC-P, IF-P, IF-F, IF-ICC, ELISA
Host:Rabbit
Clonality:Monoclonal
Target:Integrin α6 (14V4)

Brand:

CAT.NO. : ARA6862

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Size:

100μL

Trail, Bulk size or Custom requests Please contact us

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Product Details

Background

integrin subunit alpha 6(ITGA6) Homo sapiens The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],

Application

Application	Dilution Ratio
IHC-P	1:100 - 1:400
WB	1:2000 - 1:10000
IF-P/IF-F/IF-ICC	1:200 - 1:1000
ELISA	1:5000 - 1:20000

Overview

Protein Name	Integrin alpha-6
Clonality	Monoclonal
Recommended Applications	WB, IHC-P, IF-P, IF-F, IF-ICC, ELISA
Species Reactivity	Human, Mouse, Rat
Storage Buffer	PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Human Gene ID	3655
Human SwissProt No.	P23229
Mouse SwissProt No.	Q61739
Specificity	Endogenous
Reference Molecular Weight	127kDa
Predicted Molecular Weight	127kDa
Host	Rabbit
Isotype	IgG, Kappa