Ki67 Rabbit Monoclonal Antibody(ARB834)
Key features and details
- Target:
- Clone ID:
- Host:
- Molecular Weight:
- Purity:
- Species Cross-reactivity:
- Applications:
- Swissprot ID:
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Brand:
CAT.NO. : ARB6624
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Size:
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Product Details
Background
Antigen Ki-67 is a nuclear protein that is associated with and may be necessary for cellular proliferation. Furthermore, it is associated with ribosomal RNA transcription.Ki-67 was present in the nuclei of cells in the G1, S, and G2 phases of the cell division cycle as well as in mitosis. Quiescent or resting cells in the G0 phase did not express the Ki-67 antigen.Ki-67 protein was used as diagnostic tools in different types of neoplasms because it was present in all proliferating cells (normal and tumor cells) and was an excellent operational marker to determine the growth fraction of a given cell population.
Overview
| Target | Ki-67 |
| Host Species | rabbit monoclonal antibody |
| Molecular Weight | 359 kDa |
| Purity | ProA affinity purified IgG |
| Species Cross-reactivity | Human |
| Form | Liquid |
| Applications | IHC-P |
| Swissprot ID | P46013 |
| Immunogen | Synthetic peptide corresponding to Ki-67 residues within aa1000-1100 of Ki-67 |
| Storage Buffer | PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05% |
| Storage Conditions | -25°C to -18°C |
| Dilutions | IHC-P: 1:100-1:200 |
| Subcellular Location | Nucleus |
| Recommended Method | Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes |
Data
Immunohistochemical staining of human esophageal tissue sections was performed using Ki67 Rabbit Monoclonal Antibody (ARB834).
Immunohistochemical staining of human tonsillar tissue sections was performed using Ki67 Rabbit Monoclonal Antibody (ARB834).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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