L1CAM Rabbit Monoclonal Antibody(ARB979)
Key features and details
- Target:
- Clone ID:
- Host:
- Molecular Weight:
- Purity:
- Species Cross-reactivity:
- Applications:
- Swissprot ID:
-
Brand:
CAT.NO. : ARB6771
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
L1CAM, a neural cell adhesion molecule which is involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain development, L1CAM is critical in multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis. In the mature brain, L1CAM plays a role in the dynamics of neuronal structure and function, including synaptic plasticity.
L1CAM's cytoplasmic expression mainly in CNS, PNS and distal renal tubules.
L1CAM has become a marker for evaluating the malignancy and prognosis of ovarian cancer, endometrial cancer, melanoma and other tumors.
L1CAM's cytoplasmic expression mainly in CNS, PNS and distal renal tubules.
L1CAM has become a marker for evaluating the malignancy and prognosis of ovarian cancer, endometrial cancer, melanoma and other tumors.
Application
|
Application |
Dilution Ratio |
|
IHC |
1:100 - 1:200 |
Overview
|
Predicted Molecular Wt |
140kDa |
|
Species Cross-reactivity |
Human |
|
Applications |
IHC-P |
|
Purity |
ProA affinity purified IgG |
|
Form |
Liquid |
|
Swissprot ID |
P32004 |
|
Subcellular location |
Cytoplasm |
|
Recommended method |
Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18℃-25℃) for 30 minutes |
|
Storage Buffer |
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05% |
Data
Immunohistochemical staining of human colon carcinoma tissue using L1CAM Rabbit Monoclonal Antibody(ARB979)
Storage
Store at -20°C. Stable for one year from the date of shipment.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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