LXR alpha Rabbit Monoclonal Antibody(ARA934)
Key features and details
- Reactivity:Human, Mouse, Rat
- Application:WB, IHC-P
- Host:Rabbit
- Clonality:Monoclonal
- lsotype:IgG
- Target:LXR alpha
-
Brand:
CAT.NO. : ARA6772
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Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
Orphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.
Application
|
Application |
Dilution Ratio |
|
IHC-P |
1:200 - 1:1000 |
Overview
|
Antibody Type |
Recombinant Rabbit monoclonal Antibody |
|
Immunogen |
Synthetic peptide within Human LXR alpha aa 49-98 / 447 |
|
Species Reactivity |
Human, Mouse, Rat |
|
Molecular Weight |
Predicted band size: 50 kDa |
|
Conjugation |
unconjugated |
|
RRID |
AB_3070498 |
|
Form |
Liquid |
|
Storage Buffer |
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide |
|
Isotype |
IgG |
|
Purification Method |
Protein A affinity purified |
Data
Immunohistochemical analysis of paraffin-embedded human liver tissue with Rabbit anti-LXR alpha antibody at 1/200 dilution.
Storage
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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