MGMT Mouse Monoclonal Antibody(ARM633)
Key features and details
- Target:
- Clone ID:
- Host:
- Species Cross-reactivity:
- Applications:
- Dilution:
- Clonality:
-
Brand:
CAT.NO. : ARM6924
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Size:
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Product Details
Background
MGMT (O6-methylguanine-DNA methyltransferase) Involved in the cellular defense against the biological effects of O6- MeG in DNA and is transcriptionally activated in response to DNA damage and functions to repair mutagenic and cytotoxic O6-alkylguanine lesions. MGMT expression is upregulated upon ionising radiation, and high MGMT activity was associated with the presence of mutant p53.
Application
|
Application |
Dilution Ratio |
|
IHC |
1:25 - 1:100 |
Overview
|
Molecular Weight |
25 kDa |
|
Chromosome Location |
Chromosome: 10; NC_000010.10 (131265454..131565783). Location: 10q26 |
|
3D Structure |
ModBase 3D Structure for P16455 |
|
Isotype |
IgG1 |
|
Host |
Mouse |
|
Species Reactivity |
Human |
|
Purity/Purification |
Purified |
|
Form/Format |
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
|
Immunogen |
Recombinant Protein |
Data
Immunohistochemical staining of human brain tissue using MGMT Mouse Monoclonal Antibody (ARM633).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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