MGMT Rabbit Monoclonal Antibody(ARB988)
CAT.NO. : ARB6780
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
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Background
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Application
Application |
Dilution Ratio |
IHC |
1:100 - 1:200 |
Overview
Predicted Molecular Wt |
22kDa |
Species Cross-reactivity |
Human |
Applications |
IHC-P |
Purity |
ProA affinity purified IgG |
Form |
Liquid |
Swissprot ID |
P16455 |
Subcellular location |
Nucleus |
Recommended method |
Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18℃-25℃) for 30 minutes |
Immunogen |
A synthetic peptide corresponding to residues on the N-terminus of human MGMT was used as an immunogen |
Storage Buffer |
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05% |
Data

Immunohistochemical staining of human appendix tissue using MGMT Rabbit Monoclonal Antibody(ARB988)
Storage
Store at -20°C. Stable for one year from the date of shipment.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
