MMP-9 Rabbit Monoclonal Antibody(ARM526)
Key features and details
- Target:
- Clone ID:
- Host Species:
- Species Cross-reactivity:
- Applications:
- Dilution:
- Clonality:
-
Brand:
CAT.NO. : ARM6816
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
Matrix Metalloproteinase-9 (MMP-9), also known as 92-kDa Type IV Collagenase or Gelatinase B, is a member of a family of proteins involved in degradation of the extracellular matrix (ECM). After activation in inflammatory tissues, MMP-9 is produced by neutrophils, macrophages, mast cells, and stromal cells. It has also been reported that the protein may have a crucial role in angiogenesis and neovascularization. As degradation of collagen IV in the basement membrane and ECM promotes tumour progression, including invasion, metastasis, growth, and angiogenesis, MMP-9 is involved in the development of several human malignancies. Overexpression of MMP-9 has been reported in a number of different cancers, including those of the breast and colon, as well as gastric and nasopharyngeal cancers.
Application
|
Application |
Dilution Ratio |
|
IHC |
1:50 - 1:200 |
Overview
|
Molecular Weight |
78,458 Da |
|
Chromosome Location |
Chromosome: 20; NC_000020.10 (44637547..44645200). Location: 20q11.2-q13.1 |
|
3D Structure |
ModBase 3D Structure for P14780 |
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Isotype |
IgG |
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Host |
Rabbit |
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Species Reactivity |
Human |
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Purity/Purification |
Purified |
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Form/Format |
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
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Immunogen |
Recombinant Protein |
Data
Immunohistochemical staining of human diffuse large B-cell lymphoma tissue using MMP-9 Rabbit Monoclonal Antibody (ARM526).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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