MNDA Rabbit Polyclonal Antibody
Key features and details
- Reactivity:Human
- Application:IHC
- Host:Rabbit
- Clonality:Polyclonal
- Target:MNDA
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Brand:
CAT.NO. : ARA6780
RMB Please choose
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Product Details
Background
The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. [provided by RefSeq, Jul 2008]
Application
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Application |
Dilution Ratio |
|
IHC-P |
1:50-1:100 |
Overview
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Immunogen |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human MNDA. The exact sequence is proprietary. |
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Purification Method |
The antibody was purified by immunogen affinity chromatography. |
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Product Form |
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. |
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Gene Name |
MNDA |
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Related Names |
Myeloid cell nuclear differentiation antigen |
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Gene ID (Human) |
4332 |
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Protein ID (Human) |
P41218 |
Data
Immunohistochemical staining of human lymph node tissue using MNDA Rabbit Polyclonal Antibody
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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