Monkey Cardiac Troponin I ELISA Kit

Key features and details

  • 产品描述: ARG82896 Monkey Cardiac Troponin I ELISA Kit is a high sensitive Enzyme Immunoassay kit for the quantification of Monkey Cardiac Troponin I in serum, plasma and cell culture supernatants.
  • 反应物种: Mk
  • 应用: ELISA
  • 特异性: Not react with the following recombinant Monkey proteins: Adiponectin, ApoAI, BMP1, BMP2, BMP3, BMP4, BMP5, BMP7, CCL2, CCL4, CCL5, CRP, HGF, HSP27, IL-1β, IL-1RA,IL-1α, IL-1 RI, IL-2, IL-4, IL-5, IL-6, IL-6R, IL-8, IL-12, IL-13, IL-15, IL-17C, IL-21, IL-23, IFNβ, IFN-γ, PDGF, PLA2G7, prolactin, serpin E1, TGFβ1, TGFβ2,TGFβ3,TLR1, TLR2, TL3, TLR9, TNF-α, TNF RI, TNF RII, VEGF, VEGF R1.
  • 靶点名称: Cardiac Troponin I
  • 偶联标记: HRP
  • 偶联标记说明: Substrate: TMB and read at 450 nm.
  • Protein Full name: Cardiac Troponin I
  • 灵敏度: 46 pg/ml
  • Brand:
CAT.NO. : ARG82896
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Product Details
概述
产品描述ARG82896 Monkey Cardiac Troponin I ELISA Kit is a high sensitive Enzyme Immunoassay kit for the quantification of Monkey Cardiac Troponin I in serum, plasma and cell culture supernatants.
反应物种Mk
应用ELISA
特异性Not react with the following recombinant Monkey proteins: Adiponectin, ApoAI, BMP1, BMP2, BMP3, BMP4, BMP5, BMP7, CCL2, CCL4, CCL5, CRP, HGF, HSP27, IL-1β, IL-1RA,IL-1α, IL-1 RI, IL-2, IL-4, IL-5, IL-6, IL-6R, IL-8, IL-12, IL-13, IL-15, IL-17C, IL-21, IL-23, IFNβ, IFN-γ, PDGF, PLA2G7, prolactin, serpin E1, TGFβ1, TGFβ2,TGFβ3,TLR1, TLR2, TL3, TLR9, TNF-α, TNF RI, TNF RII, VEGF, VEGF R1.
靶点名称Cardiac Troponin I
偶联标记HRP
偶联标记说明Substrate: TMB and read at 450 nm.
Protein Full nameCardiac Troponin I
灵敏度46 pg/ml
样品类型Serum, plasma and cell culture supernatants.
标准范围93.75 - 6000 pg/ml
样本量100 µl
精确Intra-Assay CV: 5%
Inter-Assay CV: 8%
別名RCM1; cTnI; Cardiac troponin I; TNNC1; CMD1FF; CMD2A; Troponin I, cardiac muscle; CMH7
应用说明
检测时间~ 3 hours
属性
形式96 well
存放说明Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
基因名称TNNI3
全名troponin I type 3 (cardiac)
背景介绍Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]
生物功能Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. [UniProt]
产品亮点Related products:
Troponin antibodies; Troponin ELISA Kits;
New ELISA data calculation tool:
Simplify the ELISA analysis by GainData
翻译后修饰Phosphorylated at Ser-42 and Ser-44 by PRKCE; phosphorylation increases myocardium contractile dysfunction (By similarity). Phosphorylated at Ser-23 and Ser-24 by PRKD1; phosphorylation reduces myofilament calcium sensitivity. Phosphorylated preferentially at Thr-31. Phosphorylation by STK4/MST1 alters its binding affinity to TNNC1 (cardiac Tn-C) and TNNT2 (cardiac Tn-T). [UniProt]
检测图片 (1)
  • ARG82896 Monkey Cardiac Troponin I ELISA Kit standard curve image

    ARG82896 Monkey Cardiac Troponin I ELISA Kit results of a typical standard run with optical density reading at 450 nm.

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