Monoamine Oxidase Activity Assay Kit (Fluorometric)
CAT.NO. : ARG82183
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概述
产品描述 | ARG82183 Monoamine Oxidase Activity Assay Kit (Fluorometric) can be used to measure Monoamine Oxidase activity in biological samples and it also can be used to evaluate and screen for MAO inhibitors. (Please note that this kit does not include a microplate, MAO-A and MAO-B enzyme.) |
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反应物种 | Hu, Ms, Rat, All |
应用 | FuncSt |
靶点名称 | Monoamine Oxidase |
偶联标记说明 | Read at 530/585 nm (fluorometric) |
灵敏度 | 0.01 U/L |
样本量 | 45 µl |
別名 | MAO-A; EC 1.4.3.4; Amine oxidase [flavin-containing] A; Monoamine oxidase type A |
应用说明
应用说明 | Please note that this kit does not include a microplate, MAO-A and MAO-B enzyme. |
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检测时间 | 30 min |
属性
形式 | Liquid |
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存放说明 | Store the kit at -20°C. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # P21397 Human Amine oxidase [flavin-containing] A Swiss-port # Q64133 Mouse Amine oxidase [flavin-containing] A |
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基因名称 | MAOA |
全名 | monoamine oxidase A |
背景介绍 | This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012] |
生物功能 | Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine. [UniProt] |
细胞定位 | Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side. [UniProt] |
