Mouse ACVRL1 ELISA Kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
- 样品类型:
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Brand:
CAT.NO. : ARG81943
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Product Details
内含物
| 货号 | 内含物名称 | 包装 | 温度 |
|---|---|---|---|
| ARG81943-001 | Antibody-coated microplate | 8 X 12 strips | 4°C. Unused strips should be sealed tightly in the air-tight pouch. |
| ARG81943-002 | Standard | 2 X 10 ng/vial | 4°C |
| ARG81943-003 | Standard/Sample diluent | 30 ml (Ready to use) | 4°C |
| ARG81943-004 | Antibody conjugate concentrate (100X) | 1 vial (100 µl) | 4°C |
| ARG81943-005 | Antibody diluent buffer | 12 ml (Ready to use) | 4°C |
| ARG81943-006 | HRP-Streptavidin concentrate (100X) | 1 vial (100 µl) | 4°C |
| ARG81943-007 | HRP-Streptavidin diluent buffer | 12 ml (Ready to use) | 4°C |
| ARG81943-008 | 25X Wash buffer | 20 ml | 4°C |
| ARG81943-009 | TMB substrate | 10 ml (Ready to use) | 4°C (Protect from light) |
| ARG81943-010 | STOP solution | 10 ml (Ready to use) | 4°C |
| ARG81943-011 | Plate sealer | 4 strips | Room temperature |
概述
| 产品描述 | ARG81943 Mouse ACVRL1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Mouse ACVRL1 in serum, plasma (heparin, EDTA) and cell culture supernatants. |
|---|---|
| 反应物种 | Ms |
| 应用 | ELISA |
| 特异性 | There is no detectable cross-reactivity with other relevant proteins. |
| 靶点名称 | ACVRL1 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 23.45 pg/ml |
| 样品类型 | Serum, plasma (heparin, EDTA) and cell culture supernatants. |
| 标准范围 | 46.9 - 3000 pg/ml |
| 样本量 | 100 µl |
| 精确 | Intra-Assay CV: 7.4%; Inter-Assay CV: 8.2% |
| 別名 | ACVRLK1; ALK1; ORW2; ALK-1; HHT; EC 2.7.11.30; Serine/threonine-protein kinase receptor R3; TGF-B superfamily receptor type I; HHT2; SKR3; TSR-I; Activin receptor-like kinase 1 |
应用说明
| 检测时间 | ~ 5 hours |
|---|
属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q61288 Mouse Serine/threonine-protein kinase receptor R3 |
|---|---|
| 基因名称 | ACVRL1 |
| 全名 | activin A receptor type II-like 1 |
| 背景介绍 | This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq, Jul 2008] |
| 生物功能 | Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well. [UniProt] |
| 产品亮点 | Related products: ACVRL1 antibodies; ACVRL1 ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
检测图片 (1)
ARG81943 Mouse ACVRL1 ELISA Kit standard curve image
ARG81943 Mouse ACVRL1 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
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