Mouse BMP4 recombinant protein (Active) (His-tagged, C-ter)
Key features and details
- 产品描述:
- 应用:
- 靶点名称:
- 物种:
- A.A. 序列:
- 表达系统:
- 生物活性:
- 活性说明:
- 別名:
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Brand:
CAT.NO. : ARG70185
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Product Details
概述
| 产品描述 | E. coli expressed, His-tagged (C-ter) Active Mouse BMP4 recombinant protein |
|---|---|
| 应用 | SDS-PAGE |
| 靶点名称 | BMP4 |
| 物种 | Mouse |
| A.A. 序列 | Lys303 - Arg408 |
| 表达系统 | E. coli |
| 生物活性 | Active |
| 活性说明 | Determined by its ability to induce alkaline phosphatase production by ATDC5 cells. The ED50 for this effect is1 x 10^5 IU/mg. |
| 別名 | BMP2B; BMP-4; OFC11; Bone morphogenetic protein 2B; BMP2B1; Bone morphogenetic protein 4; MCOPS6; ZYME; BMP-2B |
属性
| 形式 | Powder |
|---|---|
| 纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | >98% (by SDS-PAGE) |
| 缓冲液 | 20 mM sodium carbonate (pH 4.5) |
| 复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | BMP4 |
|---|---|
| 全名 | bone morphogenetic protein 4 |
| 背景介绍 | The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein. [provided by RefSeq, Jul 2008] |
| 生物功能 | Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). [UniProt] |
| 细胞定位 | Secreted, extracellular space, extracellular matrix. [UniProt] |
检测图片 (1)
ARG70185 Mouse BMP4 recombinant protein (Active) (His-tagged, C-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70185 Mouse BMP4 recombinant protein (Active) (His-tagged, C-ter).
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