Mouse CD120a / TNFR1 ELISA Kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
- 样品类型:
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Brand:
CAT.NO. : ARG81675
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Product Details
内含物
| 货号 | 内含物名称 | 包装 | 温度 |
|---|---|---|---|
| ARG81675-001 | Antibody-coated microplate | 8 X 12 strips | 4°C. Unused strips should be sealed tightly in the air-tight pouch. |
| ARG81675-002 | Standard | 2 X 10 ng/vial | 4°C |
| ARG81675-003 | Standard/Sample diluent | 30 ml (Ready to use) | 4°C |
| ARG81675-004 | Antibody conjugate concentrate (100X) | 1 vial (100 µl) | 4°C |
| ARG81675-005 | Antibody diluent buffer | 12 ml (Ready to use) | 4°C |
| ARG81675-006 | HRP-Streptavidin concentrate (100X) | 1 vial (100 µl) | 4°C |
| ARG81675-007 | HRP-Streptavidin diluent buffer | 12 ml (Ready to use) | 4°C |
| ARG81675-008 | 25X Wash buffer | 20 ml | 4°C |
| ARG81675-009 | TMB substrate | 10 ml (Ready to use) | 4°C (Protect from light) |
| ARG81675-010 | STOP solution | 10 ml (Ready to use) | 4°C |
| ARG81675-011 | Plate sealer | 4 strips | Room temperature |
概述
| 产品描述 | ARG81675 Mouse CD120a / TNFR1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Mouse CD120a / TNFR1 in serum and cell culture supernatants. |
|---|---|
| 反应物种 | Ms |
| 应用 | ELISA |
| 特异性 | There is no detectable cross-reactivity with other relevant proteins. |
| 靶点名称 | CD120a / TNFR1 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 7.8 pg/ml |
| 样品类型 | Serum and cell culture supernatants. |
| 标准范围 | 15.6 - 1000 pg/ml |
| 样本量 | 100 µl |
| 精确 | Intra-Assay CV: 5.3%; Inter-Assay CV: 6.2% |
| 別名 | TNF-R; p60; TNFAR; CD antigen CD120a; TNFR55; TBP1; TNF-RI; TNFR1-d2; Tumor necrosis factor receptor superfamily member 1A; FPF; TNFR60; CD120a; TNFR1; p55; TNF-R55; TNF-R-I; MS5; TNFR-I; Tumor necrosis factor receptor 1; TBPI; Tumor necrosis factor receptor type I; TNF-R1; p55-R |
应用说明
| 检测时间 | ~ 5 hours |
|---|
属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P25118 Mouse Tumor necrosis factor receptor superfamily member 1A |
|---|---|
| 基因名称 | TNFRSF1A |
| 全名 | tumor necrosis factor receptor superfamily, member 1A |
| 背景介绍 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease. [provided by RefSeq, Jul 2008] |
| 生物功能 | Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. [UniProt] |
| 产品亮点 | Related products: CD120a antibodies; CD120a ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 翻译后修饰 | The soluble form is produced from the membrane form by proteolytic processing. [UniProt] |
检测图片 (1)
ARG81675 Mouse CD120a / TNFR1 ELISA Kit standard curve image
ARG81675 Mouse CD120a / TNFR1 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
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