Mouse CXCL7 / NAP2 (48-109) recombinant protein (Active) (His-tagged, N-ter)
Key features and details
- 产品描述:
- 应用:
- 靶点名称:
- 物种:
- A.A. 序列:
- 表达系统:
- Protein Full name:
- 生物活性:
- 活性说明:
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Brand:
CAT.NO. : ARG70440
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Product Details
概述
| 产品描述 | E. coli expressed, His-tagged (N-ter) Active Mouse CXCL7 / NAP2 recombinant protein |
|---|---|
| 应用 | SDS-PAGE |
| 靶点名称 | CXCL7 / NAP2 |
| 物种 | Mouse |
| A.A. 序列 | Ile48 - Ile109 |
| 表达系统 | E. coli |
| Protein Full name | Platelet basic protein |
| 生物活性 | Active |
| 活性说明 | Determined by its ability to chemoattract BaF3 cells transfected with human CXCR2. The ED50 for this effect is |
| 別名 | PPBP; Pro-Platelet Basic Protein; SCYB7; CTAP3; CXCL7; MDGF; LDGF; TGB1; PBP; Platelet Basic Protein; Beta-TG; CTAPIII; LA-PF4; THBGB1; B-TG1; NAP-2; TGB; Connective Tissue-Activating Peptide III; Chemokine (C-X-C Motif) Ligand 7 |
属性
| 形式 | Powder |
|---|---|
| 纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | >98% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) |
| 复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | PPBP |
|---|---|
| 全名 | Pro-Platelet Basic Protein |
| 背景介绍 | The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity. |
| 生物功能 | LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-273, NAP-274, NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation. |
| 细胞定位 | Secreted |
| 翻译后修饰 | Cleavage on pair of basic residues, Disulfide bond |
检测图片 (1)
ARG70440Mouse CXCL7 / NAP2 (48-109) recombinant protein (Active) (His-tagged, N-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70440 Mouse CXCL7 / NAP2 (48-109) recombinant protein (Active) (His-tagged, N-ter)
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