Mouse PDGF BB ELISA Kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- Protein Full name:
- 灵敏度:
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Brand:
CAT.NO. : ARG83020
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Product Details
概述
| 产品描述 | ARG83020 Mouse PDGF BB ELISA Kit is an Enzyme Immunoassay kit for the quantification of Mouse PDGF BB in serum, plasma (heparin), ascites, urine and cell culture supernatants. |
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| 反应物种 | Ms |
| 应用 | ELISA |
| 特异性 | Cross-reacts with: Rat PDGF BB. Not cross-reacts with: Human PDGF-AA. Mouse PDGF AA. Rat VEGF164, PDGF-CC. |
| 靶点名称 | PDGF BB |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| Protein Full name | Platelet-derived growth factor subunit B |
| 灵敏度 | 31.25 pg/ml |
| 样品类型 | Serum, plasma (heparin), ascites, urine and cell culture supernatants. |
| 标准范围 | 62.5 - 4000 pg/ml |
| 样本量 | 100 µl |
| 精确 | Intra-Assay CV: less than 10% Inter-Assay CV: less than 10% |
| 別名 | PDGFB, Platelet Derived Growth Factor Subunit B, Becaplermin, SSV, SIS, Platelet Derived Growth Factor Beta Polypeptide (Simian Sarcoma Viral (V Sis) Oncogene Homolog) , Platelet Derived Growth Factor Beta Polypeptide, Platelet Derived Growth Factor Subunit B, Platelet Derived Growth Factor B Chain, Proto Oncogene C Sis, PDGF Subunit B, PDGF 2 PDGF2, Platelet Derived Growth Factor, Beta Polypeptide (Oncogene SIS), Epididymis Secretory Sperm Binding Protein, Platelet Derived Growth Factor 2, PDGF, B Chain, Oncogene SIS, IBGC5, C Sis |
应用说明
| 检测时间 | ~ 4 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P31240 Mouse Platelet-derived growth factor subunit B |
|---|---|
| 基因名称 | PDGFB |
| 全名 | Platelet Derived Growth Factor Subunit B |
| 背景介绍 | This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit B, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit A. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with dermatofibrosarcoma protuberans, a rare skin tumor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015] |
| 生物功能 | Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 产品亮点 | Related products: PDGF BB antibodies; PDGF BB ELISA Kits; Related news: The role of HDGF in tumor angiogenesis New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 翻译后修饰 | Cleavage on pair of basic residues, Disulfide bond, Glycoprotein. [UniProt] |
检测图片 (1)
ARG83020 Mouse PDGF BB ELISA Kit standard curve image
ARG83020Mouse PDGF BB ELISA Kit results of standard run with optical density reading at 450 nm
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