Mouse sRANK Ligand / TNFSF11 / TRANCE ELISA Kit
Key features and details
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- 反应物种:
- 应用:
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- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
- 样品类型:
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Brand:
CAT.NO. : ARG80222
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Product Details
内含物
| 货号 | 内含物名称 | 包装 | 温度 |
|---|---|---|---|
| ARG80222-001 | Antibody-coated microplate | 8 X 12 strips | 4°C. Unused strips should be sealed tightly in the air-tight pouch. |
| ARG80222-002 | Standard (Lyophilized) | 3 X 2 ng/vial | 4°C |
| ARG80222-003 | Standard diluent buffer | 20 ml | 4°C |
| ARG80222-004 | Antibody conjugate concentrate | 400 µl | 4°C |
| ARG80222-005 | Antibody diluent buffer | 16 ml | 4°C |
| ARG80222-006 | HRP-Streptavidin concentrate | 400 µl | 4°C (Protect from light) |
| ARG80222-007 | HRP-Streptavidin diluent buffer | 16 ml | 4°C |
| ARG80222-008 | 20X Wash buffer | 50 ml | 4°C |
| ARG80222-009 | TMB substrate | 12ml | 4°C (Protect from light) |
| ARG80222-010 | STOP solution | 12ml | 4°C |
| ARG80222-011 | Plate sealer | 4 strips | Room temperature |
概述
| 产品描述 | ARG80222 Mouse sRANK Ligand / TNFSF11 / TRANCE ELISA Kit is an Enzyme Immunoassay kit for the quantification of Mouse sRANK Ligand / TNFSF11 / TRANCE in Serum, Plasma, Cell culture supernatants. |
|---|---|
| 反应物种 | Ms |
| 应用 | ELISA |
| 特异性 | No significant cross-reactivity or interference with Mouse C10 MIP-1, JE MIP-1, KC；human GRO beta, GRO gamma, RANTES |
| 靶点名称 | sRANK Ligand / TNFSF11 / TRANCE |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm |
| 灵敏度 | 15 pg/ml |
| 样品类型 | Serum, Plasma, Cell culture supernatants |
| 标准范围 | 31.25 - 2000 pg/ml |
| 样本量 | 100 µl |
| 精确 | CV: less than10% |
| 別名 | TRANCE; Osteoprotegerin ligand; CD254; sOdf; Receptor activator of nuclear factor kappa-B ligand; OPTB2; RANKL; OPGL; Tumor necrosis factor ligand superfamily member 11; hRANKL2; TNF-related activation-induced cytokine; Osteoclast differentiation factor; ODF; CD antigen CD254 |
应用说明
| 检测时间 | 4 hours |
|---|
属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # O35235 Mouse Tumor necrosis factor ligand superfamily member 11 |
|---|---|
| 基因名称 | Tnfsf11 |
| 全名 | tumor necrosis factor (ligand) superfamily, member 11 |
| 背景介绍 | This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced tra |
| 产品亮点 | Related products: New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 研究领域 | Cell Biology and Cellular Response kit; Immune System kit |
| 翻译后修饰 | The soluble form of isoform 1 derives from the membrane form by proteolytic processing (By similarity). The cleavage may be catalyzed by ADAM17. |
检测图片 (1)
ARG80222 Mouse sRANK Ligand / TNFSF11 / TRANCE ELISA Kit standard curve image
ARG80222 Mouse sRANK Ligand / TNFSF11 / TRANCE ELISA Kit results of a typical standard run with optical density reading at 450 nm.
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