MyoD1 Mouse Monoclonal Antibody(ARM911)
Key features and details
- Reactivity:Human
- Application:IHC
- Host:Mouse
- Clonality:Monoclonal
- lsotype:IgG
- Target Name:MyoD1
-
Brand:
CAT.NO. : ARM6701
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Product Details
Background
Myogenic Differentiation 1 (MyoD1) belongs to a family of myogenic helix - loop - helix transcription factors, and, when combined with myogenin, plays a key role in the myogenic or muscle differentiation pathway. MyoD1 is expressed in myoblasts and in activated satellite cells, but not in normal mature skeletal muscle or in quiescent satellite cells; Anti - MyoD1 is therefore used to identify cells that are committed to myogenesis. Anti - MyoD1 is also utilized as a biomarker for rhabdomyosarcomas, a malignant soft tissue neoplasm, often as part of a panel also including Anti - Myogenin and Anti - Desmin.
Application
IHC: 1:50-1:200
Overview
|
OMIM |
159970 |
|
3D Structure |
ModBase 3D Structure for P15172 |
|
Clonality |
Monoclonal |
|
Isotype |
IgG |
|
Host |
Rabbit |
|
Species Reactivity |
Human |
|
Specificity |
MyoD1 |
|
Purity/Purification |
Purified |
|
Form/Format |
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
|
Immunogen |
Recombinant Protein |
Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of Rhabdomyosarcoma sections labeling MyoD1 with ARM911.
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
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