Nestin Rabbit Monoclonal Antibody(ARM536)

Key features and details

Target: Nestin
Clone ID: ARM536
Host Species: Rabbit
Species Cross-reactivity: Human
Applications: IHC-P
Dilution: 1:50-1:200
Clonality: Monoclonal

Brand:

CAT.NO. : ARM6826

RMB Please choose

Size:

1mL

Trail, Bulk size or Custom requests Please contact us

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Product Details

Background

Nestin is a type IV intermediate filament protein that is expressed in dividing cells during early stages of Central Nervous System (CNS) and Peripheral Nervous System (PNS) development, as well as that of myogenic and other tissue types. Overexpression of nestin has been clinically linked to human gliomas, as well as tumours of the CNS, such as astrocytoma, ependymoma, oligodendroglioma, glioblastoma, and primitive neuroectodermal tumours. Nestin expression has also been indicated in prostatic adenocarcinoma, pancreatic ductal carcinoma, thyroid carcinoma, and mesenchymal tumours, such as gastrointestinal stromal tumour and dermatofibrosarcoma protuberans. Reports have suggested that nestin is significantly overexpressed in melanoma, and is linked to more advanced stages of the disease

Application

Application	Dilution Ratio
IHC	1:50 - 1:200

Overview

Molecular Weight	1621
3D Structure	ModBase 3D Structure for P48681
Isotype	IgG
Host	Rabbit
Species Reactivity	Human
Purity/Purification	Purified
Form/Format	Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
Immunogen	Recombinant Protein