NKX2.2 Rabbit Monoclonal Antibody(ARB506)
Key features and details
- Target:
- Clone ID:
- Host:
- Molecular Weight:
- Purity:
- Species Cross-reactivity:
- Applications:
- Swissprot ID:
-
Brand:
CAT.NO. : ARB6798
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Size:
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Product Details
Background
NKX2.2 is a homeodomain transcription factor that plays a role in neuroendocrine and glial differentiation. NKX2.2 is expressed in normal tissues, including the cerebral cortex, pancreas and stomach. Highly expressed in Ewing's sarcoma. As one of many small round blue cell tumors, Ewing's sarcoma can be difficult to diagnose due to the characteristic undifferentiated morphology. NKX2.2 has proven its utility as a sensitive maker for distinguishing Ewing's sarcoma from other round blue cell tumors when used in a panel.
Application
|
Application |
Dilution Ratio |
|
IHC-P |
1:100 - 1:200 |
Overview
| Predicted Molecular Wt | 30kDa |
| Species Cross-reactivity | Human |
| Applications | IHC-P |
| Purity | ProA affinity purified IgG |
| Form | Liquid |
| Swissprot ID | O95096 |
| Subcellular location | Nucleus |
| Recommended Method | Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18°C - 25°C) for 30 minutes |
| Storage Buffer | PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05% |
Data
Immunohistochemical staining of human Ewing sarcoma tissue sections using NKX2.2 Rabbit Monoclonal Antibody (ARB506).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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