NTRK Rabbit Monoclonal Antibody(ARM639)
Key features and details
- Target:
- Clone ID:
- Host:
- Species Cross-reactivity:
- Applications:
- Dilution:
- Clonality:
-
Brand:
CAT.NO. : ARM6930
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Size:
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Product Details
Background
Neurotrophic tyrosine kinase receptor (NTRK) is a family of 3 proto-oncogenes including NTRK1, NTRK2, and NTRK3. NTRK gene fusions have been reported in a variety of tumor types, which are involved in biological processes such as neuronal survival, differentiation, and plasticity under physiological circumstances. Recently, the FDA has approved Entrectinib for patients with NTRK fusions, thus testing for NTRK fusions identifies patients who may be candidates for NTRK inhibitor therapy.
Application
|
Application |
Dilution Ratio |
|
IHC |
1:25 - 1:100 |
Overview
|
Isotype |
IgG1 |
|
Host |
Mouse |
|
Species Reactivity |
Human |
|
Form/Format |
Tris Buffer, pH7.3-7.7, with 1% BSA and <0.1% Sodium Azide |
Data
Immunohistochemical staining of human NTRK fusion cell line positive control tissue and 293 negative cell line control tissue using NTRK Rabbit Monoclonal Antibody (ARM639).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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